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DOI 10.1016/j.jse.2009.02.016

Медицинская библиотека · Journal of shoulder and elbow surgery · 2009

Complete removal of load is detrimental to rotator cuff healing.

Galatz Leesa M, Charlton Nichole, Das Rosalina, Kim H Mike, Havlioglu Necat, Thomopoulos Stavros

Сравнительное исследованиеСтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

HYPOTHESIS: This study evaluated the effect of the mechanical environment on the healing rotator cuff by paralyzing the supraspinatus muscle in the operative shoulder of a rat model of rotator cuff injury and repair.

METHODS

Unilateral shoulders of rats underwent a supraspinatus injury and repair. Botulinum toxin A was used to paralyze the muscle after repair. Postoperatively, 1 group was immobilized and 1 group was allowed free range of motion. Saline-injected, casted rats were used as the control group. Repairs were evaluated histologically, geometrically, and biomechanically.

RESULTS

Specimens from the saline-injected rats had greater scar volume and cross-sectional area of the repair compared with the paralyzed groups. Structural properties were increased in the saline group compared with the paralyzed groups. Free range of motion (ie, uncasted group) resulted in modest improvements in biomechanical properties but did not obviate the effect of paralysis.

CONCLUSIONS

Complete removal of load was detrimental to rotator cuff healing, especially when combined with immobilization.

Для цитирования: Galatz Leesa M, Charlton Nichole, Das Rosalina, Kim H Mike, Havlioglu Necat, Thomopoulos Stavros. Complete removal of load is detrimental to rotator cuff healing.. Journal of shoulder and elbow surgery. 2009. DOI: 10.1016/j.jse.2009.02.016.

Предметные рубрики MeSH

AnimalsBiomechanical PhenomenaBiopsy, NeedleBotulinum Toxins, Type ADisease Models, AnimalImmobilizationImmunohistochemistryMaleMuscle, SkeletalProbabilityRandom AllocationRatsRats, Sprague-DawleyRecovery of FunctionReference ValuesRotator CuffRotator Cuff InjuriesSensitivity and SpecificityTendon InjuriesWeight-BearingWound Healing
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