Management of Traumatic Brain Injury Sequelae With Alpha-2 Adrenergic Receptor Agonists.

OBJECTIVE

To describe clinical uses of the class of alpha-2 receptor agonist medications in the treatment of traumatic brain injury sequelae. Clinicians treating patients with traumatic brain injuries (TBI) will often see patients who have been prescribed alpha-2 agonists or may consider initiating use.

DESIGN

Narrative review.

CONCLUSION

This class of medication has a number of different indications (and side effects), and drugs within this class also have some unique properties that can be important factors in clinical decision-making. Although this class of medications has been available for many years, there is still much emerging information that is pertinent for the treatment of patients with TBI.