Glaucoma in an eye with situs inversus of the optic disc.

Situs inversus of the optic disc is a congenital abnormality characterized by dysversion of the optic nerve head and surrounding retinal vessels. Here, we report the retinal nerve fiber layer (RNFL) characteristics of eyes with situs inversus of the optic discs with and without glaucoma, as imaged using spectral-domain optical coherence tomography (OCT). OCT findings of an eye with situs inversus of optic disc and uveitic glaucoma revealed abnormal RNFL thinning. After six months of treatment, progressive RNFL thinning in the superior-nasal and inferior-nasal areas was found. The fellow eye with situs inversus of the optic disc without glaucoma showed a thicker nasal RNFL, a thinner temporal RNFL, and more nasally located RNFL peak locations compared with normative database. RNFL thickness characteristics in eyes with situs inversus of the optic discs, presented here, should be considered when assessing glaucoma in eyes with this abnormality.