Genome-wide analyses of susceptibility genes responsible for mandibular prognathism in the Japanese population.

BACKGROUND

Mandibular prognathism (MP) is a type of malocclusion characterized by an imbalance in the anteroposterior position of the upper and lower jaws. The prevalence of MP in Japan is relatively high, suggesting a unique genetic background in the population.

HIGHLIGHT: Genome-wide analyses identified susceptibility genes responsible for mandibular prognathism in the Japanese population.

CONCLUSION

Identification of the genes associated with malocclusion will pave the way for personalized and precise medicine and contribute to craniofacial biology.