Soft imperceptible wearable electronics for at-home cardiovascular monitoring of infants with single ventricle heart disease.

Patients with single ventricle heart disease (SVHD) require multiple palliative surgeries. Due to high mortality rates observed during the four to sixth-month interstage period between the first and second surgery, at-home monitoring practices are important. However, modern-day interstage monitoring does not offer comprehensive quantitative tracking of health conditions since it relies on logging the infant's weight, feeding patterns, and oxygen saturation once a day in a journal. Here, we introduce a soft wearable electronic device for the home monitoring of SVHD patients. The ultrathin, imperceptible, wireless system is designed for safe integration with infants' delicate skin. The system features a chest-mounted biopatch and forehead-mounted pulse oximeter, streaming real-time data to a cloud-based platform. This smart device has built-in alert functions to help caregivers recognize when the patients should be returned to the hospital for in-person observation, easing decision-making from non-clinically trained personnel. In addition, the patient-tailored database also improves the communication between the home and hospital, reducing the load on caretakers during this stressful period.