Role of Chlamydia trachomatis and herpes simplex virus in cervicitis and female infertility.

A population of infertile women attending the infertility clinic of Ain Shams university hospital were studied with the purpose of assessing the possible role of C. trachomatis and Herpes simplex virus as factors related to their infertility and coexisting Cervicitis. A control group of fertile women was also examined. C. trachomatis antigen detected by ELISA was found in 2 patients with tubal obstruction and one patient with infertility with normal tube and 3 patients of Control group. The difference between the 3 groups is statistically insignificant. No Cases were recorded positive for Herpes simplex virus infection. C. trachomatis antibodies titer was statistically significant between the 3 groups at titer 1/16, 1/64, 1/256. This study suggests the possibility that high titer of IgG antibody, may serve as a marker of deeply seated infection of C. trachomatis.