[Prediction of renal transplantation outcome using artificial neural networks and investigating important risk factors].

BACKGROUND

Renal Transplantation is the final choice for some patients with ESRD (End-Stage Renal Disease), but some transplantations suffer from acute or chronic rejection, so its very important to predict the outcome of transplantation.

METHOD: s. The dataset was extracted from records of 4572 patients with kidney transplantations. We applied an Artificial Neural Network (ANN) model to predict transplantation outcome. Moreover, novel features have been explored which enhanced the prediction performance.

RESULTS

The results show that the well configured neural networks can predict renal transplant outcome with a sensitivity and specificity of higher than 86%. The results show creatinine is the most important risk factor that affects the renal transplantation outcome.

CONCLUSION

The designed neural networks can properly predict the transplantation outcome with the accuracy of 86%. Recipient creatinine is the most important variable in the prediction of the renal outcome.