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DOI 10.1136/archdischild-2020-319250

Медицинская библиотека · Archives of disease in childhood · 2020

Estimated effect of secondary screening for hip dislocation.

Wenger Daniel, Tiderius Carl Johan, Düppe Henrik

СтатьяПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

OBJECTIVES

To quantify the effect of secondary screening for hip dislocations.

DESIGN

Retrospective analysis of hospital files from participants in a prospectively collected nationwide registry.

SETTING

Child healthcare centres and orthopaedic departments in Sweden.

PARTICIPANTS

Of 126 children with hip dislocation diagnosed later than 14 days age in the 2000-2009 birth cohort, 101 had complete data and were included in the study.

INTERVENTIONS: The entire birth cohort was subject to clinical screening for hip instability at 6-8 weeks, 6 months and 10-12 months age. Children diagnosed through this screening were compared with children presenting due to symptoms, which was used as a surrogate variable representing a situation without secondary screening.

MAIN OUTCOME MEASURES: Age at diagnosis and disease severity of late presenting hip dislocations.

RESULTS

Children diagnosed through secondary screening were 11 months younger (median: 47 weeks) compared with those presenting with symptoms (p<0.001). Children diagnosed through secondary screening had 11% risk of having a high (severe) dislocation, compared with 38% for those diagnosed due to symptoms; absolute risk reduction 27% (95% CI: 9.7% to 45%), relative risk 0.28 (95% CI: 0.11 to 0.70). Children presenting due to symptoms had OR 5.1 (95% CI: 1.7 to 15) of having a high dislocation, and OR 11 (95% CI: 4.1 to 31) of presenting at age 1 year or older, compared with the secondary screening group. The secondary screening was able to identify half of the children (55%, 95% CI: 45% to 66%) not diagnosed through primary screening.

CONCLUSIONS

Secondary screening at child healthcare centres may have substantially lowered the age at diagnosis in half of all children with late presenting hip dislocation not diagnosed through primary screening, with the risk of having a high dislocation decreased almost to one-quarter in such cases.

Для цитирования: Wenger Daniel, Tiderius Carl Johan, Düppe Henrik. Estimated effect of secondary screening for hip dislocation.. Archives of disease in childhood. 2020. DOI: 10.1136/archdischild-2020-319250.

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