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DOI 10.1038/s41598-025-19879-7

Медицинская библиотека · Scientific reports · 2025

Development, validation and visualization of risk prediction model for postoperative shivering in patients undergoing video-assisted thoracoscopic lobectomy: a real-world retrospective study.

Xia Fuhai, Li Qiang, Cheng Zhineng, Yan Qing, Hu Juan, Liu Junshi, Li Gui, Chen Rui, Zhang Jing, Li Jing

СтатьяВалидационное исследованиеПеревод в очереди

Аннотация

To develop, validate, and visualize a risk prediction model for postoperative shivering in patients undergoing video-assisted thoracoscopic (VATS) lobectomy, addressing the lack of individualized tools for this high-risk population. This retrospective study analyzed 530 patients undergoing VATS lobectomy from a tertiary hospital in Wuhan (January 2022-December 2023). The data were randomly divided into training set and validation set at a ratio of 7∶3. Patients were stratified into postoperative shivering (n = 198) and non-postoperative shivering (n = 332) groups based on Bedside Shivering Assessment Scale (BSAS) criteria. Logistic regression identified independent risk factors, and a nomograph was developed. Model performance was evaluated using the area under the receiver operating characteristic curve (AUC), calibration curves, Hosmer-Lemeshow test, and decision curve analysis (DCA). An online visualization tool was created for clinical implementation. Postoperative shivering occurred in 198 of 530 patients undergoing VATS lobectomy (37.36%). The logistic regression analysis identified age < 60 years, intraoperative hypothermia, delayed anesthesia recovery, absence of postoperative analgesia, operation duration > 180 min and lower preoperative temperature as significant risk factors for postoperative shivering (P < 0.05). The resulting nomograph demonstrated strong discrimination with AUCs of 0.847 (95%CI: 0.809-0.885) in the training cohort (n = 424) and 0.836 (95%CI: 0.747-0.925) in validation (n = 106), while calibration curves and the Hosmer-Lemeshow test (χ2 = 13.123, P = 0.108) confirmed model reliability. DCA demonstrated clinical utility across threshold probabilities of 0.20-0.98. In order to promote clinical implementation, deployment of the visualization tools online ( https://shivering.shinyapps.io/dynnomapp/ ), which supports dynamic risk assessment. This study established the first risk prediction model for postoperative shivering in patients undergoing VATS lobectomy, integrating six perioperative variables into a clinically applicable nomograph and online tool. The model facilitates identification of high-risk patients, enabling targeted interventions to mitigate shivering-related complications.

Для цитирования: Xia Fuhai, Li Qiang, Cheng Zhineng, Yan Qing, Hu Juan, Liu Junshi, Li Gui, Chen Rui, Zhang Jing, Li Jing. Development, validation and visualization of risk prediction model for postoperative shivering in patients undergoing video-assisted thoracoscopic lobectomy: a real-world retrospective study.. Scientific reports. 2025. DOI: 10.1038/s41598-025-19879-7.

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