[Relationship between urticaria-like toxic allergic exanthema and infection by toxin-producing Staphylococcus strains in infants].

The author observed that in the throat and/or nasal culture of approximately 80% of little children admitted to hospital with urticaria-like toxic-allergic exanthem, exotoxin-producing strains of Staphylococcus aureus could be isolated. In 15 of the 19 cases presented. Toxic Shock Syndrome Toxin (TSST-1) and in 4 cases various enterotoxins were identified. With aimed antibiotic treatment the skin symptoms of the children healed up in 3-4 days. Thus, the following question is raised: when facing the Toxic Shock Syndrome Toxin for the first time, why do children develop only skin symptoms, without severe complications of the Toxic Shock Syndrome observed in adult patients. It is assumed that similarly to classic infectious diseases, the course of the illness is milder in little childhood and the frequency of complications are lower than in adulthood. This phenomenon may be attributed to the immature immune reactivity of little children.