Intrauterine resuscitation during labor: should maternal oxygen administration be a first-line measure?

Intrauterine resuscitation techniques are often used during labor when the fetal heart rate pattern is nonreassuring. These techniques have not been well studied; common practices are based on classic studies many years old. Models of intrauterine resuscitation using one (or more) technique as a first-line intervention and adding others in a specific series or clinical algorithm based on fetal response have not been tested. Maternal oxygen therapy is often used; however, recent evidence suggests potential risks to the mother and fetus or newborn. Even small increases in maternal and fetal pO(2) as a result of maternal oxygen administration can produce oxygen free radical activity in mothers and fetuses. The potential long-term effects are unknown. Caution should be exercised when considering maternal oxygen administration as a first-line intrauterine resuscitation measure until more data are available, reserving its use after other measures have been unsuccessful in resolving the nonreassuring fetal heart rate pattern.