[Modified IFA assay in diagnosis of legionellosis].

IFA and modified IFA assay were used for the antigen-antibody reaction between L. pneumophila type I, II to VI and their anti-sera as well as anti-sera of other related bacteria, and between 31 strains of pneumonic pathogens and various types of Lp-antisera. The same results were obtained by using these two methods. 46 pneumonia cases with paired sera and 116 normal sera were examined for Lp-antibody. The results obtained by both were almost the same. It was shown that the modified IFA assay was sensitivity and specific as the original one, and it could be used in laboratory for the diagnosis of Legionellosis.