Toxic Epidermal Necrolysis Induced by Doxycycline: A Case Report and Literature Review.

Lyell syndrome, also known as toxic epidermal necrolysis (TEN), is a rare but life-threatening skin condition, often triggered by certain medications. Antiepileptics, allopurinol, and some nonsteroidal anti-inflammatory drugs are the most common causes. Some antibiotics are also common culprits, although tetracyclines are rarely linked to this condition. We hereby report a case of TEN induced by doxycycline in an 18-year-old girl who was taking the drug for the treatment of acne.