Legionnaires' disease associated with acute encephalomyelitis.

A 26-year-old man had Legionnaires' disease associated with encephalomyelitis and abnormal CSF. Neurologic symptoms antedated the appearance of the pulmonary infiltrate and have persisted despite appropriate antibiotic therapy. A review of the literature revealed only one other similar case. Legionnaires' disease should be considered in the differential diagnosis of encephalomyelitis even in the absence of a pneumonic infiltrate.