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DOI 10.1186/s13098-026-02111-5

Медицинская библиотека · Diabetology & metabolic syndrome · 2026

Effectiveness of chewing gum on blood glucose level among pregnant women with gestational diabetes: a randomized controlled clinical trial.

Zanussi Perimah Pasha, Samakoosh Shayan Abedi, Mohsenzadeh-Ledari Farideh, Fili Romina, Omidvar Shabnam, Abbaszadeh Soheila, Gholinia Hemmatollah, Meftah Neda

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Аннотация

AIMS: Chewing gum could play a role in managing hyperglycemia in individuals with diabetes. The study evaluated the effects of chewing gum on blood sugar management in women diagnosed with Gestational Diabetes Mellitus (GDM).

METHODS

This open-label, single-center randomized controlled clinical trial enrolled 100 women recently diagnosed with GDM. Participants received either standard care or an additional chewing gum intervention. Self-monitored blood glucose (SMBG) levels were recorded over a period of five days.

RESULTS

The gum-chewing group consistently exhibited notably lower mean postprandial blood glucose (PPG) and fasting blood glucose levels compared to the control group. The estimated mean differences (intervention vs. control group) were: -7.86 mg/dl, p = 0.053 (fasting blood glucose); -13.2 mg/dl, p = 0.022 (breakfast); -8.92 mg/dl, p = 0.014 (lunch); -12.96 mg/dl, p = 0.006 (dinner).

CONCLUSIONS

To summarize, notable variations in blood glucose levels were identified between the groups, indicating that chewing gum serves as an effective alternative approach to reducing high blood sugar in women with GDM.

Для цитирования: Zanussi Perimah Pasha, Samakoosh Shayan Abedi, Mohsenzadeh-Ledari Farideh, Fili Romina, Omidvar Shabnam, Abbaszadeh Soheila, Gholinia Hemmatollah, Meftah Neda. Effectiveness of chewing gum on blood glucose level among pregnant women with gestational diabetes: a randomized controlled clinical trial.. Diabetology & metabolic syndrome. 2026. DOI: 10.1186/s13098-026-02111-5.
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