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DOI 10.1111/jocn.17715

Медицинская библиотека · Journal of clinical nursing · 2025

Clinically Significant Functional Impairments and Symptoms in COVID-19 Survivors: Empirical Research Quantitative.

Tang Chia-Chun, Wu Wei-Wen, Ho Sung-Jung, Liu Wang-Da, Pan Mei-Yan, Chang Shih-Chieh, Wang Wei-Shin, Yeh Yi-Chen, Chen Cheng-Hsuan, Chang Jung-Chen

СтатьяМногоцентровое исследованиеНаблюдательное исследованиеПоддержка исследования: вне правительства СШАПеревод в очереди

Аннотация

BACKGROUND

COVID-19 survivors may experience complex, distressing and persistent symptoms, referred to as long COVID, lasting months or years after diagnosis. More evidence is needed for effective long COVID screening and management.

AIM: To explore the clinical profile of long COVID and factors associated with its development.

DESIGN

A multicentre correlational study using a cross-sectional design.

METHODS

Adults diagnosed with COVID-19 6-9 months earlier were recruited via social media and referrals from three facilities. Participants provided demographic data and assessed their symptoms and functional status using validated questionnaires. Data were analysed using descriptive statistics and binomial logistic regression.

RESULTS

Among 102 participants, 13%-30% reported significant impairments in cognitive, emotional and physical functioning. Over 10% experienced symptoms such as diarrhoea, sleep problems, dyspnoea, nausea, fatigue and pain. These impairments and symptoms were associated with acute symptom severity, chronic disease, overweight status, regular exercise and living without partners.

CONCLUSION

This study adds to the literature by examining long-term functional status and symptoms in omicron survivors using comprehensive, validated tools. The findings highlight the prevalence and clinical significance of long COVID symptoms, aiding in the identification of functional impairments requiring medical and nursing interventions.

IMPLICATIONS FOR THE PROFESSION AND PATIENT CARE: Nurses should recognise these symptoms and educate survivors about potential challenges. Policies addressing long-term issues, including research, health services and education, are essential.

REPORTING METHOD: This study follows the STROBE guideline (Table S1).

PATIENT OR PUBLIC CONTRIBUTION: Patients self-reported symptoms for this study.

TRIAL REGISTRATION: ClinicalTrials.gov (NCT05303103).

Для цитирования: Tang Chia-Chun, Wu Wei-Wen, Ho Sung-Jung, Liu Wang-Da, Pan Mei-Yan, Chang Shih-Chieh, Wang Wei-Shin, Yeh Yi-Chen, Chen Cheng-Hsuan, Chang Jung-Chen. Clinically Significant Functional Impairments and Symptoms in COVID-19 Survivors: Empirical Research Quantitative.. Journal of clinical nursing. 2025. DOI: 10.1111/jocn.17715.

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