Syphilis Update.

Cases of syphilis in the United States are at an all-time high. Although men who have sex with men continue to be adversely affected, record rates of infection are now seen in women, men who have sex with women, and in congenital cases. Persons of color and ethnic minorities are among communities affected. Review of sexual practices and risk factors such as substance use are key to identifying infections early to stop spread of the disease. Educating nurses on how to identify those at risk, order and interpret testing, effectively treat, and follow these patients is vital to stopping the epidemic.