The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2019
The role of trace element, mineral, vitamin and total antioxidant status in women with habitual abortion.
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Sami Awaz Sayfallah, Suat Ekin, Alkis Ismet, Karakus Yagmur, Guler Seyithan
Аннотация
OBJECTIVE: In this study, women with habitual abortus (HA) and healthy control groups were determined for zinc (Zn), copper (Cu), manganese (Mn), selenium (Se), iron (Fe), cobalt (Co), chromium (Cr), nickel (Ni), lead (Pb), magnesium (Mg), calcium (Ca), sodium (Na), potassium (K), retinol, cholecalciferol, α-tocopherol, phylloquinone, total antioxidant (TAS) and total oxidation status (TOS) levels, also, and the relationships of these variables with HA were evaluated.
MATERIAL AND METHODS: The study included 39 women with HA and 39 healthy control subjects. In this study, trace element and mineral analyses by ICP-OES and vitamin analyses were determined using HPLC method.
RESULTS: Statistical analysis found that in the HA group was significantly lower than the control group with regarding cholecalciferol, phylloquinone, TAS, Se, Zn, Cu, Mg, K and Na levels (p < .05, p < .01, p < .01, p < .001, p < .05, p < .05, p < .01, p < .01 and p < .05). However, HA group was also significantly higher than control group regards to TOS, OSI and Ca⁄Mg levels (p < .05, p < .001, p < .05). In the HA group, significantly positive correlations were observed between phylloquinone and Ca (r = 0.495; p = .027), also, indicates negative significant correlation between cholecalciferol and Co (r = -0.598; p = .031).
CONCLUSION: Our findings indicate that the results could be helpful in the monitoring of women with HA in terms of deficiency. It is important that in terms of the evaluation of phylloquinone, cholecalciferol Se, Zn, Cu, Mg and Ca/Mg ratio is required to consider.
MATERIAL AND METHODS: The study included 39 women with HA and 39 healthy control subjects. In this study, trace element and mineral analyses by ICP-OES and vitamin analyses were determined using HPLC method.
RESULTS: Statistical analysis found that in the HA group was significantly lower than the control group with regarding cholecalciferol, phylloquinone, TAS, Se, Zn, Cu, Mg, K and Na levels (p < .05, p < .01, p < .01, p < .001, p < .05, p < .05, p < .01, p < .01 and p < .05). However, HA group was also significantly higher than control group regards to TOS, OSI and Ca⁄Mg levels (p < .05, p < .001, p < .05). In the HA group, significantly positive correlations were observed between phylloquinone and Ca (r = 0.495; p = .027), also, indicates negative significant correlation between cholecalciferol and Co (r = -0.598; p = .031).
CONCLUSION: Our findings indicate that the results could be helpful in the monitoring of women with HA in terms of deficiency. It is important that in terms of the evaluation of phylloquinone, cholecalciferol Se, Zn, Cu, Mg and Ca/Mg ratio is required to consider.