Explore (New York, N.Y.) · 2026
Effect of inhaled peppermint essential oil aromatherapy on postoperative nausea and vomiting in patients undergoing laparoscopic gynecologic surgery.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Tang Hai, Liu Mengyu, Zhou Zijian, Liu Hui, Ji Zhijie, Yang Min, Shen Jinfeng, Zhang Maoyin
Аннотация
BACKGROUND: This study evaluated the effect of inhaled peppermint essential oil (PEO) aromatherapy on postoperative nausea and vomiting (PONV) in patients undergoing laparoscopic gynecologic surgery.
METHODS: In this randomized controlled trial, 106 patients were assigned to either the PEO group or normal saline (NS) group. The PEO group received inhalational aromatherapy with 2% peppermint oil before induction, preoperatively, and immediately after extubation. The NS group received an identical intervention using 2 ml of 0.9% sodium chloride solution.
RESULTS: Compared with the NS group, the PEO group had a significantly lower incidence of PONV within 24 h (52.8% vs. 73.6%; p = 0.043). The reduction was most notable during the first hour (45.3% vs. 73.6%; p = 0.047). The PEO group also demonstrated significantly improved anxiety scores at 0-24 h and 24-48 h, reduced pain catastrophizing, and decreased abdominal distension.
CONCLUSION: Inhaled peppermint aromatherapy reduced the incidence of PONV, improved anxiety, decreased pain catastrophizing, and alleviated abdominal distension in patients undergoing laparoscopic gynecological surgery.
CLINICAL TRIAL REGISTRATION: This study was registered in the Chinese Clinical Trial Registry. (Registration number: ChiCTR2400093289 Registration Date:2024-12-02).
METHODS: In this randomized controlled trial, 106 patients were assigned to either the PEO group or normal saline (NS) group. The PEO group received inhalational aromatherapy with 2% peppermint oil before induction, preoperatively, and immediately after extubation. The NS group received an identical intervention using 2 ml of 0.9% sodium chloride solution.
RESULTS: Compared with the NS group, the PEO group had a significantly lower incidence of PONV within 24 h (52.8% vs. 73.6%; p = 0.043). The reduction was most notable during the first hour (45.3% vs. 73.6%; p = 0.047). The PEO group also demonstrated significantly improved anxiety scores at 0-24 h and 24-48 h, reduced pain catastrophizing, and decreased abdominal distension.
CONCLUSION: Inhaled peppermint aromatherapy reduced the incidence of PONV, improved anxiety, decreased pain catastrophizing, and alleviated abdominal distension in patients undergoing laparoscopic gynecological surgery.
CLINICAL TRIAL REGISTRATION: This study was registered in the Chinese Clinical Trial Registry. (Registration number: ChiCTR2400093289 Registration Date:2024-12-02).