Development of a Chitosan-Based Wound Dressing from Shrimp Shells Incorporated with Ethanol Extracts of Fruit Peels for Inhibiting Staphylococcus aureus and Staphylococcus epidermidis Infections.

BACKGROUND

Bacterial infections caused by Staphylococcus aureus and Staphylococcus epidermidis continue to pose a significant challenge to global healthcare. To assess its antibacterial efficacy, this study aimed to develop a wound dressing composed of shrimp shell-derived chitosan combined with extracts from fruit peels, specifically tangerine, mangosteen, and banana peel.

METHODS

Bioactive compounds were extracted using ethanol, and the minimum inhibitory concentration (MIC) against the bacteria was determined.

RESULTS

Among the extracts tested, mangosteen peel demonstrated the highest efficacy (MIC = 0.39 mg/mL for S. epidermidis) compared to tangerine and banana peels. Evaluation of the developed wound dressings revealed that those containing mangosteen peel extract exhibited the largest bacterial inhibition zones.

CONCLUSIONS

These findings highlight the potential of agricultural waste materials to create sustainable and ecofriendly medical products.