Glycemic profile assessment during betamethasone administration in women with twin pregnancies after IVF with or without gestational diabetes.

BACKGROUND AND AIMS: Betamethasone's effect on glycemia in twin pregnancies, with or without gestational diabetes mellitus, has not been adequately investigated.

METHODS

We assessed the glycemic profile of 30 women with twin pregnancies after in-vitro-fertilization who were given betamethasone.

RESULTS

The majority of women were treated eventually with insulin to maintain glycemia. In insulin-treated women the increase in insulin dosage was of 61.1%. Insulin use/dosage was not associated with betamethasone dose, age, gestational age, weight gain in pregnancy, or duration of hyperglycemia.

CONCLUSION

Post-betamethasone, twin pregnancies seem to follow the same glycemia pattern as singleton pregnancies.