Tomography (Ann Arbor, Mich.) · 2026
Characteristic MR Signal of Velopharyngeal-Related Muscles on Cine-MRI in Patients with Oral Cancers and Preserved Swallowing Function: An Exploratory Feasibility Study.
СтатьяНазвание и аннотация: Перевод в очереди
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Nishimura Shun, Oda Masafumi, Hayakawa Mana, Tabe Shirou, Tsurushima Hiroki, Nishina Susumu, Iwawaki-Otsuka Kozue, Wakasugi-Sato Nao, Matsumoto-Takeda Shinobu, Takahashi Osamu, Haraguchi Kazuya, Yoshii Shinji, Habu Manabu, Yoshioka Izumi, Kagawa Toyohiro, Morimoto Yasuhiro
Аннотация
BACKGROUND/OBJECTIVES: Surgically treated oral cancer patients often face velopharyngeal insufficiency, which adversely impacts their quality of life (QOL). Our past investigations revealed noticeable MR signal shifts in velopharyngeal-related muscles during water deglutition on CMR among healthy individuals. We hypothesized that analyzing these distinct signal fluctuations could offer a novel visual perspective for detecting deglutition anomalies in surgical oral cancer cases. This feasibility study aimed to assess velopharyngeal-related muscular performance via CMR in post-operative oral cancer patients.
METHODS: Nineteen patients with oral malignancies were prospectively evaluated pre- and post-operatively. Twelve quantitative CMR metrics alongside subjective dysphagia scores were investigated. We analyzed whether signal intensity (SI) ratio alterations in these muscles correlated with dysphagia severity and clinical parameters.
RESULTS: Although three specific CMR parameters significantly worsened post-operatively, muscle MR signal values increased during deglutition without significant variation between pre- and post-surgical states. Subjective swallowing assessments remained entirely normal across all subjects.
CONCLUSIONS: This preliminary investigation indicates that CMR can visualize stable velopharyngeal-related muscle activity after surgery in oral cancer patients maintaining adequate swallowing status. Nevertheless, confirmation via larger, symptomatic patient cohorts alongside gold-standard techniques remains mandatory.
METHODS: Nineteen patients with oral malignancies were prospectively evaluated pre- and post-operatively. Twelve quantitative CMR metrics alongside subjective dysphagia scores were investigated. We analyzed whether signal intensity (SI) ratio alterations in these muscles correlated with dysphagia severity and clinical parameters.
RESULTS: Although three specific CMR parameters significantly worsened post-operatively, muscle MR signal values increased during deglutition without significant variation between pre- and post-surgical states. Subjective swallowing assessments remained entirely normal across all subjects.
CONCLUSIONS: This preliminary investigation indicates that CMR can visualize stable velopharyngeal-related muscle activity after surgery in oral cancer patients maintaining adequate swallowing status. Nevertheless, confirmation via larger, symptomatic patient cohorts alongside gold-standard techniques remains mandatory.