The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques · 2004
Modafinil in endozepine stupor. A case report.
Клинический случайСтатьяНазвание и аннотация: Перевод в очереди
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Scott Sharon, Ahmed Iftekhar
Аннотация
BACKGROUND: Endozepine-4 stupor is a rare disorder. It presents with recurrent episodes of stupor and coma. Endozepine-4 levels are elevated during an attack with electroencephalogram showing fast activity during the ictal phase. There is no specific treatment and various drugs have been tried without long-term benefit.
METHOD: We used the vigilance promoting drug modafinil to prevent such attacks in a case presented with endozepine stupor.
RESULTS: The vigilance promoting drug modafinil prevented recurrent episodes of stupor and coma in this patient at a dose of 200 mg/day for a period of six months. Upon withdrawal of the drug, the patient experienced recurrent episodes and on reinstitution of modafinil she has remained asymptomatic in the following one year.
METHOD: We used the vigilance promoting drug modafinil to prevent such attacks in a case presented with endozepine stupor.
RESULTS: The vigilance promoting drug modafinil prevented recurrent episodes of stupor and coma in this patient at a dose of 200 mg/day for a period of six months. Upon withdrawal of the drug, the patient experienced recurrent episodes and on reinstitution of modafinil she has remained asymptomatic in the following one year.