The importance of domperidone (Motilium) in controlling postoperative nausea and vomiting.

Comparative study was performed for assessing the postoperative anti-emetic and emesis preventive effect of domperidone. It has been found that the emesis preventive effect of Motilium tablet is identical with the effect of the well known Daedalon (Dramamin) and Torecan. From the therapeutic aspect it is of value especially in controlling nausea and in the prevention of subsequent vomiting following the use of rectal anti-emetics. This difference is attributable to the oral route of administration. Considering the lack of toxic effects domperidone is the most favourable.