Biomarkers and testing in pathology.

PURPOSE OF REVIEW: We try to highlight the most current testing methods in uropathology. Most of these tests are not fully approved, but nevertheless have found their way to daily routine.

RECENT FINDINGS: In the bladder, testing is mainly based on immunohistochemistry and somatic testing. Other organs such as the prostate, the kidney, and the testis require sometimes different methods.

SUMMARY: Although pathology is still the gold standard in diagnosis of tumor for patients in uropathology, many clinicians want to improve treatment options and try to tailor personalized treatments. This is of course depending not only on the available treatment options, but also on the somatic or germcell background of the patient and his tumor.