Environment international · 2026
Exposure to bisphenol analogues and risk of anemia in young adults.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Chang Tien-Jyun, Chiu Chi-Yin, Huang Po-Chin, Chen Pau-Chung, Guo Yue-Leon, Cheng Tsun-Jen, Hwang Jing-Shiang, Su Ta-Chen
Аннотация
BACKGROUND: Bisphenol A (BPA) and its analogues are widely used endocrine disruptors. Their potential role in anemia remains unclear.
METHODS: We conducted a cross-sectional study of 940 adults aged 19-44 years from the Young Taiwanese Cohort (2017-2019) to assess associations of urinary bisphenol A and analogues (BPAF, BPS, BPF, BPB) with hematological indices and anemia risk. Urinary bisphenols were quantified, and hematological parameters including hemoglobin (Hb), hematocrit (Hct), mean corpuscular indices, ferritin, total iron-binding capacity (TIBC), serum iron, and transferrin saturation (TSAT) were analyzed using single- and multi-pollutant regression models to explore exposure effects and sex, age, and body mass index (BMI)-specific differences.
RESULTS: Prevalence of anemia, iron deficiency, and iron deficiency anemia (IDA) was 8.9% (13.7% in women, 2.5% in men), 16.9% (28.0% in women, 1.8% in men), and 5.9% (9.2% in women, 1.3% in men), respectively. Higher urinary BPAF, BPS, and BPF were associated with lower hemoglobin, hematocrit, ferritin, and serum iron, and higher odds of anemia and iron-deficiency anemia. Associations were stronger in women.
CONCLUSION: Exposure to BPA substitutes (BPAF, BPS, BPF) was associated with disrupted iron metabolism and increased anemia risk, particularly in women.
METHODS: We conducted a cross-sectional study of 940 adults aged 19-44 years from the Young Taiwanese Cohort (2017-2019) to assess associations of urinary bisphenol A and analogues (BPAF, BPS, BPF, BPB) with hematological indices and anemia risk. Urinary bisphenols were quantified, and hematological parameters including hemoglobin (Hb), hematocrit (Hct), mean corpuscular indices, ferritin, total iron-binding capacity (TIBC), serum iron, and transferrin saturation (TSAT) were analyzed using single- and multi-pollutant regression models to explore exposure effects and sex, age, and body mass index (BMI)-specific differences.
RESULTS: Prevalence of anemia, iron deficiency, and iron deficiency anemia (IDA) was 8.9% (13.7% in women, 2.5% in men), 16.9% (28.0% in women, 1.8% in men), and 5.9% (9.2% in women, 1.3% in men), respectively. Higher urinary BPAF, BPS, and BPF were associated with lower hemoglobin, hematocrit, ferritin, and serum iron, and higher odds of anemia and iron-deficiency anemia. Associations were stronger in women.
CONCLUSION: Exposure to BPA substitutes (BPAF, BPS, BPF) was associated with disrupted iron metabolism and increased anemia risk, particularly in women.