The Effect of Aligning Childhood Influenza Vaccination with Specific Well-Visits in a Primary Care Institution in Singapore.

Background/Objectives: Influenza vaccination in young children reduces the incidence of influenza-related complications. Compared to other vaccines in the Singapore National Childhood Immunization Schedule (NCIS), there is low influenza vaccine uptake rate among young children. Our retrospective database study aimed to evaluate the effect of aligning childhood influenza vaccination to coincide with specific well-visits in the primary care setting. Methods: A retrospective interrupted time series study was conducted on two cohorts of children aged 6 to 12 months (n = 10,082 before, and n = 9234 after). The delivery schedule was aligned with routine touchpoints to administer Dose 1 of the influenza vaccine at the 6-month well-visit and Dose 2 at the 7-month visit. Results: Dose 1 influenza vaccination rates increased from 4.7% before the intervention to 73.7% after the intervention. The proportion of children who completed two doses of the influenza vaccines increased from 3.6% to 62%. Median age at Dose 1 influenza vaccine, and completion of two doses of influenza vaccine decreased from 8.7 to 7.6 months and 9.9 to 7.7 months, respectively. Conclusions: Aligning influenza vaccination with specific well-visits substantially improves uptake, completion rates, and timeliness of vaccination, demonstrating a scalable system-level strategy to enhance immunization coverage in primary care.