Correlation of serum ferritin, D dimer and CRP levels with disease severity among hospitalized patients in India.

Delayed recognition of severe disease in hospitalized patients remains a major challenge and contributes to increased morbidity and mortality. Therefore, it is of interest to evaluate the correlation of serum ferritin, C-reactive protein (CRP) and D-dimer levels with disease severity in hospitalized patients. Hence, a hospital-based cross-sectional study was conducted on 100 adult patients and biomarker levels were measured using standard laboratory methods. The results showed a significant increase in serum ferritin, CRP and D-dimer levels with increasing disease severity (p < 0.001). A strong positive correlation was observed between these biomarkers and disease severity, with D-dimer showing the highest correlation and elevated levels were significantly associated with ICU admission and mortality. Thus, combined assessment of ferritin, CRP and D-dimer is a simple and reliable approach for early risk stratification and prognostication in hospitalized patients.