Transcatheter Mitral Valve Replacement Using a Dedicated Mitral Valve System.

BACKGROUND

Mitral valve regurgitation is a highly prevalent disease in the older population that causes significant morbidity and mortality.

CASE SUMMARY: A 77-year-old man presented with worsening functional class and asthenia. A transthoracic and transesophageal echocardiography showed severe mitral regurgitation (MR). The patient underwent a transcatheter mitral replacement procedure.

DISCUSSION: The treatment of severe MR in patients with high surgical risk remains a clinical challenge. Transcatheter mitral edge-to-edge repair is an established therapy in secondary MR; however, transcatheter mitral valve replacement (TMVR) may be an option in some patients with nonoptimal anatomic features such as degenerative MR. Cardiac computed tomography planification is needed to guide the procedure and reduce potential complications.

TAKE-HOME MESSAGES: TMVR is a feasible and effective alternative in patients with severe degenerative MR, high surgical risk, and unfavorable anatomy for edge-to-edge repair. The Cardiovalve system enables fully transfemoral transseptal TMVR with a low-profile design, achieving effective MR reduction while minimizing the risk of left ventricular outflow tract obstruction.