Ten advances defining sudden cardiac death.

Recent advances in the field of sudden cardiac death (SCD) include the recognition that 50% of SCD occurs as initial presentation of any heart disease and that many of these individuals may have been considered to be low risk. The presenting dysrhythmia in patients with cardiac arrests has changed over time such that pulseless electrical activity and asystole is more frequently encountered as compared with ventricular tachyarrhythmias. While the use of implantable defibrillators has been a tremendous advance in patients at risk for ventricular tachyarrhythmias, the use of automatic external defibrillators and wearable defibrillators is a recent advance that allows for potential SCD prevention in more patients. Finally, the area of medical genetics is an evolving discipline, which may enable clinicians to better individualize therapy for patients with genetic predispositions to cardiac dysrhythmias.