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Journal of pediatric surgery · 2013

Esophageal atresia: data from a national cohort.

СтатьяМногоцентровое исследованиеНазвание и аннотация: Перевод в очереди
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Sfeir Rony, Bonnard Arnaud, Khen-Dunlop Naziha, Auber Frederic, Gelas Thomas, Michaud Laurent, Podevin Guillaume, Breton Anne, Fouquet Virginie, Piolat Christian, Lemelle Jean Louis, Petit Thierry, Lavrand Frederic, Becmeur Francis, Polimerol Marie Laurence, Michel Jean Luc, Elbaz Frederic, Habonimana Eric, Allal Hassan, Lopez Emmanuel, Lardy Hubert, Morineau Marianne, Pelatan Cécile, Merrot Thierry, Delagausie Pascal, de Vries Philline, Levard Guillaume, Buisson Phillippe, Sapin Emmanuel, Jaby Olivier, Borderon Corinne, Weil Dominique, Gueiss Stephane, Aubert Didier, Echaieb Anais, Fourcade Laurent, Breaud Jean, Laplace Christophe, Pouzac Myriam, Duhamel Alain, Gottrand Frederic

Аннотация

PURPOSE: A prospective national register was established in 2008 to record all new cases of live-birth newborns with esophageal atresia (EA). This epidemiological survey was recommended as part of a national rare diseases plan.

METHODS: All 38 national centers treating EA participated by completing for each patient at first discharge a questionnaire validated by a national committee of experts. Data were centralized by the national reference center for esophageal anomalies. Quantitative and qualitative analyses were performed, with P-values of less than 0.05 considered statistically significant. Results of the 2008-2009 data collection are presented in this report.

RESULTS: Three hundred seven new living cases of EA were recorded between January 1, 2008, and December 31, 2009. The male/female sex ratio was 1.3, and the live-birth prevalence of EA was 1.8 per 10,000 births. Major characteristics were comparable to those reported in the literature. Survival was 95%, and no correlation with caseload was noted.

CONCLUSIONS: Epidemiologic surveys of congenital anomalies such as EA, which is a rare disease, provide valuable data for public health authorities and fulfill one important mission of reference centers. When compared with previous epidemiological data, this national population-based registry suggests that the incidence of EA remains stable.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты