Vestnik rentgenologii i radiologii · 2013
[Scintigraphic evaluation of impairments in cardiopulmonary hemodynamics and renal functional activity in patients with coronary heart disease and circulatory failure].
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Lishmanov Iu B, Vesnina Zh V, Krivonogov N G
Аннотация
OBJECTIVE: To evaluate the relationship between impairments in cardiopulmonary hemodynamics and renal functional activity in patients with circulatory failure, by applying radionuclide studies.
MATERIAL AND METHODS: Sixty-nine patients with coronary heart disease (mean age 53.23 +/- 0.87 years) with the development of NYHA functional classes II-III chronic HF were examined. To calculate cardiopulmonary hemodynamic parameters, all the patients underwent 99mTc pertechnetate radiocardiopulmonography. Their renal functional activity was assessed by dynamic radionuclide renal scintigraphy using 99mTc-DTPA.
RESULTS: The examinees had most abnormal systemic and pulmonary hemodynamic parameters. Renal dysfunction was detected in 74% of the examinees and reflected by decreased glomerular filtration rates in one or both kidneys and/or a longer tracer elimination half-life from the renal parenchyma. Stepwise regression analysis established a strong inverse correlation between impaired pulmonary circulation, on the one hand, and reduced renal filtration, on the other, and a direct correlation of impairments in renal filtration and evacuation with both left and right ventricular contractility.
CONCLUSION: Radionuclide studies are the methods of choice for diagnosis of the cardiorenal continuum.
MATERIAL AND METHODS: Sixty-nine patients with coronary heart disease (mean age 53.23 +/- 0.87 years) with the development of NYHA functional classes II-III chronic HF were examined. To calculate cardiopulmonary hemodynamic parameters, all the patients underwent 99mTc pertechnetate radiocardiopulmonography. Their renal functional activity was assessed by dynamic radionuclide renal scintigraphy using 99mTc-DTPA.
RESULTS: The examinees had most abnormal systemic and pulmonary hemodynamic parameters. Renal dysfunction was detected in 74% of the examinees and reflected by decreased glomerular filtration rates in one or both kidneys and/or a longer tracer elimination half-life from the renal parenchyma. Stepwise regression analysis established a strong inverse correlation between impaired pulmonary circulation, on the one hand, and reduced renal filtration, on the other, and a direct correlation of impairments in renal filtration and evacuation with both left and right ventricular contractility.
CONCLUSION: Radionuclide studies are the methods of choice for diagnosis of the cardiorenal continuum.
Предметные рубрики MeSH
Cardiovascular SystemFemaleGlomerular Filtration RateHeart FailureHemodynamicsHumansMaleMiddle AgedMyocardial ContractionMyocardial IschemiaPulmonary CirculationRadionuclide ImagingRadiopharmaceuticalsRenal CirculationRenal InsufficiencySeverity of Illness IndexSodium Pertechnetate Tc 99mStatistics as TopicTechnetium Tc 99m Pentetate