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International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022

Prevention of pre-eclampsia with aspirin: A systematic review of guidelines and evaluation of the quality of recommendation evidence.

Систематический обзорСтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
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Ninan Kiran, Ali Rifaa, Morfaw Frederick, McDonald Sarah D

Аннотация

BACKGROUND: Evidence has shown significant benefits of aspirin for preventing pre-eclampsia.

OBJECTIVES: The objective of this study was to systematically review recommendations from clinical practice guidelines and other recommendation documents on aspirin for the prevention of pre-eclampsia.

SEARCH STRATEGY: Ten databases were searched for statements from December 1, 2013, to January 1, 2022.

SELECTION CRITERIA: Without language restrictions, the most recent version of documents was considered.

DATA COLLECTION AND ANALYSIS: Two authors independently extracted recommendations. Guideline quality was assessed using a modified AGREE-II instrument and the AGREE-REX tool.

MAIN RESULTS: Out of 48 statements on the prevention of pre-eclampsia, 46 had recommendations on use of aspirin. Of them, 39 were supported by evidence from systematic reviews or randomized controlled trials. Three statements reported aspirin's significant reductions in preterm pre-eclampsia and one in perinatal death. Concerning quality, 41% of statements were rated as high quality in all domains of the AGREE-II tool, 15% were rated high quality in all domains of the AGREE-REX tool, and 11% were rated high quality in all domains on both tools.

CONCLUSIONS: While 96% of statements advocated for use of aspirin, only 9% reported a significant reduction in preterm pre-eclampsia or perinatal death. Based on the AGREE tools, future statements could use methodological improvement.

Предметные рубрики MeSH

ИП Урсолов Владлен Сергеевич

ИНН 500118482352 · ОГРНИП 314500117700049

Реквизиты и контакты