Machine learning approaches for asthma disease prediction among adults in Sri Lanka.

Objectives

Addressing the challenge of cost-effective asthma diagnosis amidst diverse symptom patterns among patients, this study aims to develop a machine learning-based asthma prediction tool for self-detection of asthma.

Methods

Data from 6,665 participants in the Sri Lanka Health and Ageing Study (2018-2019) are used for this research. Thirteen machine learning algorithms, including Logistic Regression, Support Vector Machine, Decision Tree, Random Forest, Naïve Bayes, K-Nearest Neighbors, Gradient Boost, XGBoost, AdaBoost, CatBoost, LightGBM, Multi-Layer Perceptron, and Probabilistic Neural Network, are employed.

Results

A hybrid version of Logistic Regression and LightGBM outperformed other models, achieving an AUC of 0.9062 and 79.85% sensitivity. Key predictive features for asthma include wheezing, breathlessness with wheezing, shortness of breath attacks, coughing attacks, chest tightness, nasal allergies, physical activity, passive smoking, ethnicity, and residential sector.

Conclusion

Combining Logistic Regression and LightGBM models can effectively predict adult asthma based on self-reported symptoms and demographic and behavioural characteristics. The proposed expert system assists clinicians and patients in diagnosing potential asthma cases.