Uncovering the Presentation and Diagnosis of Human Bocavirus in a Patient at a Tertiary Care Center: A Case Report.

A toddler, thriving well, developmentally normal, and fully immunized, presented with fever, cough, and cold for a day, followed by breathing difficulty. Although the child was not ill upon admission, he had a fever and was breathing rapidly. On examination, visible sub-costal retractions and wheezing in both lungs were noted. He required Intensive Care Unit (ICU) management for a brief period, with oxygen supplementation, round-the-clock nebulization, and other supportive care. Initially, he was diagnosed with a wheeze-associated lower respiratory tract infection, as his chest X-ray showed bilateral hyperinflated lung fields. Blood investigations revealed microcytic hypochromic anemia, and his renal function tests, electrolytes, and liver function tests were within normal limits. C-reactive protein (CRP) was positive at 15.1 mg/L (≥10 mg/L considered positive), and the blood culture was sterile. A nasopharyngeal swab on day 2 of admission tested positive for reverse transcription-polymerase chain reaction (RT-PCR) of Human Bocavirus (HBoV). Gradually, the child's condition improved, and he was able to be taken off oxygen support two days after admission. Upon discharge, the child was managed symptomatically with oral medications.