JNCI cancer spectrum · 2026
Race, ethnicity, and prior colorectal screening test use in CONFIRM colonoscopy vs fecal immunochemical testing trial participants.
СтатьяРандомизированное исследованиеСравнительное исследованиеНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Robertson Douglas J, Dominitz Jason A, Beed Alexander, Boardman Kathy, Del Curto Barbara J, Guarino Peter D, Huang Grant D, Imperiale Thomas F, LaCasse Andrew, Larson Meaghan, Gupta Samir, Lieberman David, Planeta Beata, O'Leary Timothy J, Shaukat Aasma, Sultan Shanaz, Kyriakides Tassos C, CONFIRM Study Group
Аннотация
BACKGROUND: Colorectal cancer (CRC) outcomes vary by race and ethnicity, and screening test use may contribute to this variation. We examined the association of race, ethnicity, and associated factors with CRC screening test use in a setting where financial barriers to screening are mitigated.
METHODS: Survey information was gathered from US veteran participants (n = 50 125) when enrolled into a randomized trial comparing screening colonoscopy to annual fecal immunochemical testing in the prevention of CRC mortality. The primary exposures of interest were the participants' self-identified race and ethnicity, with adjustment for variables capturing access to care. Multivariable logistic regression, stratified by site and age, was used to assess the relationship between exposures of interest and prior use of any CRC screening test, prior colonoscopy, and prior fecal occult blood test (including fecal immunochemical testing) use.
RESULTS: Screening test use was common (n = 28 330 [56.5%]), with more veterans reporting prior fecal occult blood testing (n = 20 386 [40.7%]) than prior colonoscopy (n = 12 671 [25.3%]). In multivariable analysis, Black participants were more likely (odds ratio [OR] = 1.06, 95% confidence interval [CI] = 1.01 to 1.12) to have had any prior screening relative to White persons, and this finding was driven by more frequent fecal occult blood testing use relative to White persons (OR = 1.16, 95% CI = 1.10 to 1.23). There was no association between Hispanic ethnicity (relative to White persons) on the primary outcomes.
CONCLUSIONS: In this cohort, prior screening test use was common, with observed variation in overall test use by race, but not ethnicity. Further study of CRC screening test use in diverse populations is needed.
CLINICALTRIALS.GOV ID: NCT#05612347 (https://clinicaltrials.gov/study/NCT05612347).
METHODS: Survey information was gathered from US veteran participants (n = 50 125) when enrolled into a randomized trial comparing screening colonoscopy to annual fecal immunochemical testing in the prevention of CRC mortality. The primary exposures of interest were the participants' self-identified race and ethnicity, with adjustment for variables capturing access to care. Multivariable logistic regression, stratified by site and age, was used to assess the relationship between exposures of interest and prior use of any CRC screening test, prior colonoscopy, and prior fecal occult blood test (including fecal immunochemical testing) use.
RESULTS: Screening test use was common (n = 28 330 [56.5%]), with more veterans reporting prior fecal occult blood testing (n = 20 386 [40.7%]) than prior colonoscopy (n = 12 671 [25.3%]). In multivariable analysis, Black participants were more likely (odds ratio [OR] = 1.06, 95% confidence interval [CI] = 1.01 to 1.12) to have had any prior screening relative to White persons, and this finding was driven by more frequent fecal occult blood testing use relative to White persons (OR = 1.16, 95% CI = 1.10 to 1.23). There was no association between Hispanic ethnicity (relative to White persons) on the primary outcomes.
CONCLUSIONS: In this cohort, prior screening test use was common, with observed variation in overall test use by race, but not ethnicity. Further study of CRC screening test use in diverse populations is needed.
CLINICALTRIALS.GOV ID: NCT#05612347 (https://clinicaltrials.gov/study/NCT05612347).