Schizophrenia research · 2020
Impaired memory for temporal context in schizophrenia patients with hallucinations and thought disorganisation.
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Brébion Gildas, Stephan-Otto Christian, Cuevas-Esteban Jorge, Usall Judith, Ochoa Susana
Аннотация
INTRODUCTION: Context processing deficiencies have been established in patients with schizophrenia and it has been proposed that these deficiencies are involved in the formation of positive symptoms.
METHOD: We administered a temporal context discrimination task to 60 schizophrenia patients and 60 healthy individuals. Pictures were presented in two sessions separated by half an hour and the participants were required to remember afterwards whether the pictures had been presented in the first or the second session.
RESULTS: The number of temporal context errors was significantly increased in the patient group. More specifically, it was highly significantly increased in a subgroup of patients presenting hallucinations, while the patients without hallucinations were equivalent to the healthy individuals. Regression analyses revealed that, independently of memory of the pictures themselves, verbal and visual hallucinations, as well as thought disorganisation, were associated with more temporal context errors. In contrast, affective flattening and anhedonia were associated with fewer of these errors.
CONCLUSION: Inability to process or remember the temporal context of production of events might be a mechanism underlying both hallucinations and thought disorganisation.
METHOD: We administered a temporal context discrimination task to 60 schizophrenia patients and 60 healthy individuals. Pictures were presented in two sessions separated by half an hour and the participants were required to remember afterwards whether the pictures had been presented in the first or the second session.
RESULTS: The number of temporal context errors was significantly increased in the patient group. More specifically, it was highly significantly increased in a subgroup of patients presenting hallucinations, while the patients without hallucinations were equivalent to the healthy individuals. Regression analyses revealed that, independently of memory of the pictures themselves, verbal and visual hallucinations, as well as thought disorganisation, were associated with more temporal context errors. In contrast, affective flattening and anhedonia were associated with fewer of these errors.
CONCLUSION: Inability to process or remember the temporal context of production of events might be a mechanism underlying both hallucinations and thought disorganisation.