The Multifaceted Benefits of Triphala: Uncovering Phytochemical and Pharmacological Properties From Antiquity to Modern Times.

Most Ayurvedic drugs are polyherbal formulations. Amongst Triphala, a widely utilised Ayurvedic formulation, is available globally as a health promoting agent. It consists of more than 150 bioactive compounds that work synergistically and restore the physiological balance. The term Triphala implies the meaning of three fruits, that is, Tri-three, Phala-fruit. The outer pericarp of the fruits of Haritaki (Terminalia chebula), Vibhitaki (Terminalia bellirica), and Amalaki (Emblica officinalis) is grouped as Triphala. It is indicated in the treatment of a wide disease spectrum, like pyrexia, integumentary disease, diabetes mellitus, wound healing, dentistry, angiogenesis, arthritis, protection against radiation, cancer, and so forth. The multidimensional health benefits of Triphala are mainly due to the presence of several phytochemicals like ellagic acid, chebulinic acid, gallic acid, corilagin, and so forth. However, only a few comprehensive reviews have been published on the phytochemistry and pharmacology of Triphala so far. Therefore, in this review, we have provided an in-depth exploration of Triphala, tracing its reported uses from ancient Ayurvedic traditions to modern scientific understanding. We have discussed its key bioactive molecules, presented evidence of its diverse pharmacological activities, examined its relevance to current disease groups, and outlined future research directions in detail.