Neurourology and urodynamics · 2020
ICI-RS 2019 nocturia think tank: How can experimental science guide us in understanding the pathophysiology of nocturia?
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Vahabi Bahareh, Jabr Rita, Fry Chris, McCloskey Karen, Everaert Karel, Agudelo Christina W, Monaghan Thomas F, Rahnama'i Mohammad S, Panicker Jalesh N, Weiss Jeffrey P
Аннотация
INTRODUCTION: The following is a report on the proceedings of the 2019 International Consultation on Incontinence-Research Society nocturia think tank (NTT).
OBJECTIVES: The objectives of the 2019 NTT were as follows: (a) to evaluate the role of urothelium in the pathophysiology of nocturia; (b) to determine whether nocturia is a circadian disorder; (c) to discuss the role of melatonin in nocturia; (d) to consider ambulatory urodynamic monitoring in evaluating patients with nocturia; (e) to explore studies of water handling in human compartments utilizing heavy water; and (f) to explore whether basic science is the key to understanding the treatment options for diminished bladder capacity in patients with nocturia.
METHODS: A compendium of discussions of the role of experimental science in understanding the pathophysiology of nocturia is described herein.
RESULTS AND CONCLUSIONS: Translational science will play an increasing role in understanding the pathophysiology of nocturia, which may result in improved treatment strategies.
OBJECTIVES: The objectives of the 2019 NTT were as follows: (a) to evaluate the role of urothelium in the pathophysiology of nocturia; (b) to determine whether nocturia is a circadian disorder; (c) to discuss the role of melatonin in nocturia; (d) to consider ambulatory urodynamic monitoring in evaluating patients with nocturia; (e) to explore studies of water handling in human compartments utilizing heavy water; and (f) to explore whether basic science is the key to understanding the treatment options for diminished bladder capacity in patients with nocturia.
METHODS: A compendium of discussions of the role of experimental science in understanding the pathophysiology of nocturia is described herein.
RESULTS AND CONCLUSIONS: Translational science will play an increasing role in understanding the pathophysiology of nocturia, which may result in improved treatment strategies.