International journal of epidemiology · 2025
Association between dairy intake and all-cause and cause-specific mortality: a pooled analysis of 0.4 million Japanese adults from 10 population-based cohort studies.
СтатьяНазвание и аннотация: Перевод в очереди
Обработка статьи · этапы, ошибки и управление
Загрузка состояния…
Ошибки и ограничения
История · было → стало
Состояние обновляется каждые 5 секунд, пока блок открыт. Процент показывается только там, где известен объём работы. Пауза останавливает продолжение этапа; текущий запрос к источнику может завершиться.
Lu Yukai, Sugawara Yumi, Hozawa Atsushi, Iwasaki Motoki, Sawada Norie, Kanehara Rieko, Oze Isao, Ito Hidemi, Miyagawa Naoko, Koyanagi Yuriko N, Wada Keiko, Nagata Chisato, Ge Sanyu, Kitamura Tetsuhisa, Kimura Takashi, Tamakoshi Akiko, Utada Mai, Matsuo Keitaro, Lin Yingsong, Abe Sarah Krull, Inoue Manami, Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan
Аннотация
BACKGROUND: The association between dairy intake and mortality remains unclear, particularly in populations with low dairy consumption, such as the Japanese population. Thus, we investigated the associations between dairy intake and mortality in a pooled analysis of 10 Japanese cohorts.
METHODS: We analysed data from 180 267 males and 218 423 females aged ≥35 years at baseline (1983-2014) without a history of cardiovascular disease (CVD) or cancer. Dairy consumption (milk, yogurt, cheese, and total dairy intakes) was assessed through self-reported food frequency questionnaires. Multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated for each study and pooled by using random-effects models to evaluate the associations with all-cause and cause-specific mortality.
RESULTS: Over 11.5-24.4 years of follow-up, 41 218 males and 28 659 females died. In males, compared with consuming milk <once/week, almost daily was associated with reduced all-cause mortality (HR: 0.94, 95% CI: 0.92-0.97; P-trend < .0001), CVD mortality (HR: 0.89, 95% CI: 0.82-0.97; P-trend = .005), and cerebrovascular disease mortality (HR: 0.81, 95% CI: 0.75-0.87; P-trend < .0001). In females, almost daily milk consumption was associated with reduced cerebrovascular disease mortality (HR: 0.90, 95% CI: 0.82-0.98; P-trend = .009). The second and third quartiles of total dairy intake were associated with reduced all-cause mortality in both sexes, and cancer mortality in males, although no dose-response association was found. No associations were observed for yogurt or cheese intake in either sex.
CONCLUSION: Dairy intake, particularly daily milk intake, may reduce mortality risk, especially cerebrovascular disease mortality risk, in Japanese males and females.
METHODS: We analysed data from 180 267 males and 218 423 females aged ≥35 years at baseline (1983-2014) without a history of cardiovascular disease (CVD) or cancer. Dairy consumption (milk, yogurt, cheese, and total dairy intakes) was assessed through self-reported food frequency questionnaires. Multivariable-adjusted hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated for each study and pooled by using random-effects models to evaluate the associations with all-cause and cause-specific mortality.
RESULTS: Over 11.5-24.4 years of follow-up, 41 218 males and 28 659 females died. In males, compared with consuming milk <once/week, almost daily was associated with reduced all-cause mortality (HR: 0.94, 95% CI: 0.92-0.97; P-trend < .0001), CVD mortality (HR: 0.89, 95% CI: 0.82-0.97; P-trend = .005), and cerebrovascular disease mortality (HR: 0.81, 95% CI: 0.75-0.87; P-trend < .0001). In females, almost daily milk consumption was associated with reduced cerebrovascular disease mortality (HR: 0.90, 95% CI: 0.82-0.98; P-trend = .009). The second and third quartiles of total dairy intake were associated with reduced all-cause mortality in both sexes, and cancer mortality in males, although no dose-response association was found. No associations were observed for yogurt or cheese intake in either sex.
CONCLUSION: Dairy intake, particularly daily milk intake, may reduce mortality risk, especially cerebrovascular disease mortality risk, in Japanese males and females.