[The prevalence of allergy-related symptoms and their risk factorinvestigation in early life].

Objective:The aim of this study is to investigate the incidence of allergy-related symptoms and the associated risk factors.Method:There were 205 children aged 3 to 4 years old recruited for this study.Questionnaires on skin,wheezing and rhinitis symptoms were answered,and total IgE and specific IgE in serum against house dust mite extracts were tested.Logistic regression analysis with which we calculated odds ratio(OR) and 95% confidence interval(95%CI) were used for risk factor analysis.Result:Questionnaire results show that the reported history of symptoms was 43%(88 cases) for lactation eczema and 25%(51 cases) for wheezing.The currently reported symptoms was 19%(38 cases) for frequent skin rashes,16% (33 cases) for frequent wheezing and 46%(95 cases) for rhinitis symptoms.There are 33% (68 cases) of the children reported with no symptoms currently.The lactation eczema history(OR［95%CI］:2.76［1.10-3.40］,P<0.05)and wheezing history(OR［95%CI］:2.40［1.22-4.73］,P<0.01)are both the risk factors for developing rhinitis symptoms.Serology test shows that house dust mite IgE prevalence is 24%,which is the risk factor developing rhinitis symptom(OR［95%CI］:2.10［1.09-4.07］,P<0.05).But it has nothing to do with wheezing symptom.Conclusion:Lactation eczema and house dust mite sensitization are the risk factors for developing respiratory diseases in early childhood.The house dust mite allergic respiratory symptom starts with rhinitis symptom.