Journal of anesthesia and translational medicine · 2026
Expert consensus on the application of nonsteroidal anti-inflammatory drugs for perioperative analgesia.
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Zhao Shuai, Zhao Yingying, Xie Min, Liu Yanhong, Cheng Cen, Lei Qian, Zhang Bing, Song Xuemin, Liu Xuesheng, Luo Foquan, Ji Fuhai, Xia Zhongyuan, Yang Jianjun, Chen Xiangdong, Task Force on Expert Consensus on Application of Nonsteroidal Anti-inflammatory Drugs for Perioperative Analgesia
Аннотация
Although nonsteroidal anti-inflammatory drugs (NSAIDs) have been widely used in multimodal pain management under the concept of enhanced recovery after surgery (ERAS), adverse reactions and safety events caused by their unreasonable use have become increasingly prominent. Drawing on the latest literature and evidence-based medicine domestically and abroad, and based on the research and practice frontiers of domestic perioperative analgesia, this working group has reached a consensus on several key domain-including the application regimens of NSAIDs for perioperative analgesia, drug interactions, and precautions as well as prevention strategies in special populations-yielding 12 definitive recommendations. This consensus aims to provide guidance for the standardized selection and application of NSAIDs for perioperative analgesia, and to further promote the rational, safe, and effective use of NSAIDs.