Effectiveness of Risk-Stratified Evidence-Based Nursing at Different Time Points in Cirrhosis with Upper Gastrointestinal Bleeding.

To explore the application effect of evidence-based nursing intervention under different time risk scores in patients with liver cirrhosis complicated by upper gastrointestinal bleeding (UGIB). 103 patients with cirrhosis complicated by UGIB hospitalized (June 1, 2024 to January 1, 2025) were enrolled. They were pseudo-randomly divided into a study group (n = 52) and a control group (n = 51) according to the odd-even order of enrollment (odd numbers assigned to the study group, even numbers to the control group). The control group received basic nursing care, whereas the study group received evidence-based nursing interventions guided by time-dependent risk stratification; 100 valid cases were ultimately included for analysis. The primary outcome was self-care ability, assessed using the exercise of self-care agency scale (ESCA). Secondary outcomes included quality of life, treatment efficacy, nursing satisfaction, and complication rates. Between-group comparisons were performed using t-tests and chi-square tests as appropriate. To control for Type I error due to multiple comparisons, the Bonferroni correction was applied, with statistical significance set at P < 0.01 for secondary outcomes. Following the intervention, the study group demonstrated significantly higher scores than the control group in operational skills (41.38 ± 4.62 vs. 33.06 ± 3.89, P < 0.001), health knowledge level (55.16 ± 6.49 vs. 50.38 ± 7.55, P = 0.001), and self-concept (25.38 ± 2.06 vs. 20.78 ± 1.95, P < 0.001). Additionally, the study group exhibited superior outcomes in the physical (62.68 ± 9.52 vs. 56.64 ± 8.08, P = 0.001), psychological (61.80 ± 6.87 vs. 52.80 ± 7.46, P < 0.001), and environmental (65.20 ± 7.22 vs. 59.28 ± 9.21, P < 0.001) domains of quality of life. Furthermore, the study group achieved higher treatment efficacy (84.0% vs. 64.0%, P = 0.023) and nursing satisfaction (94.0% vs. 78.0%, P=0.021) than the control group. The results showed that, based on risk stratification at different time points, evidence-based nursing can effectively enhance patients' self-care capacity and quality of life, promote recovery, and improve nursing satisfaction.