Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2013
Complete mole in a dichorionic twin pregnancy after intracytoplasmic sperm injection.
Клинический случайСтатьяОбзорНазвание и аннотация: Перевод в очереди
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Ferraz Tiago José Santos de Matos, Bartosch Carla Maria Magno, Ramalho Carla Maria Almeida, Carvalho Filipa Abreu Gomes de, Carvalho Berta Cecília Campos Lima de, Brandão Otília Gonçalves Bento Cavaleiro, Montenegro Nuno Aires Mota Mendonça
Аннотация
A dichorionic twin pregnancy with complete hydatidiform mole and coexistent fetus is a rare and challenging situation, whose pathogenesis has not been yet fully understood. We present a case of a 39-year-old woman who underwent intracytoplasmic sperm injection with two embryos transfer. The 12-week gestation ultrasound examination revealed normal fetus and placenta with features of hydatidiform mole, leading to pregnancy termination. Autopsy and histological examinations diagnosed a complete mole coexisting with a normal fetus, and the genetic analysis showed a diploid fetus with biparental genome and molar tissue with paternal diploidy. This case highlighted that complete molar pregnancies may still occur even though pregnancy is achieved after intracytoplasmic sperm injection. A review of the literature was performed by collecting data from the few similar reported cases and by commenting on the pathogenesis of this rare condition.