[Glycerol kinase deficiency in adult patient: hypertriglyceridemia resistance to diet and pharmacological treatment].

CASE REPORT: we present an 85-year-old patient with polydipsia, polyuria and severe hypertriglyceridemia of 27 years of evolution, without pancreatitis, resistant to dietary and pharmacological treatments. He was diagnosed of hyperglycerolemia due to glycerol kinase deficiency (GKD) based on: transparent non-lipemic serum, with glycerol increase in plasma and urine, without glycerol 3 phosphate increase, and a deletion, not previously described, in the glycerol kinase gene.

DISCUSSION: a correct dietary treatment with frequent meals and rich in complex carbohydrates, without medication, improved the symptomatology.