Potentiometric and spectroscopic characterization of uridine and its derivatives complexes.

Ternary systems of copper(II) ions complexes with glucuronic acid and uridine or uridine derivatives (Urd, UMP, UDP, UTP) and binary systems of tested ligands have been investigated. Potentiometric measurements in aqueous solution were performed using computer analysis. Potentiometric studies allowed the determination of the composition of the complex compounds studied and the overall stability constants. UV-Vis, EPR, 13C NMR and 31P NMR spectroscopic studies allowed the composition of the internal coordination sphere to be determined and the types of chromophores to be identified. MLL', ML(H)L' and MLL'(OH) (L - Urd, UMP, UDP or UTP; L' - GluA) complexes were observed in the systems studied.