Archives of physical medicine and rehabilitation · 2026
What Is the Optimal Timing for Intradialytic Resistance Exercise? A Randomized Controlled Trial.
СтатьяРандомизированное исследованиеНазвание и аннотация: Перевод в очереди
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Bingölbali Ömer, Oğuz Semra
Аннотация
OBJECTIVE: This study aimed to examine the impact of intradialytic resistance exercise timing on blood pressure, physical performance, and muscle strength in patients on hemodialysis.
DESIGN: A single-blind, randomized controlled clinical trial.
SETTING: Hospital-based hemodialysis unit.
PARTICIPANTS: Forty-two patients (N=42) on hemodialysis were randomly assigned to early- or late-exercise groups.
INTERVENTIONS: Both groups performed the same resistance exercise protocol during either the first or last 2 hours of dialysis for 8 weeks.
MAIN OUTCOME MEASURES: The primary outcomes were postdialysis systolic blood pressure and the number of intradialytic hypotensive episodes. Secondary outcomes included physical performance and lower extremity muscle strength.
RESULTS: Postdialysis systolic blood pressure declined less in the late-exercise group than in the early exercise group (interaction effect: -5.4 mmHg; 95% CI, -10.72 to -0.25; P<.05). No significant difference in the number of intradialytic hypotensive episodes was observed between the groups (P>.05). Both groups showed significant improvements in blood pressure, heart rate, and physical performance (P<.05). Significant improvement was observed only in the left quadriceps femoris muscle in both groups (P<.05).
CONCLUSIONS: Resistance exercise performed in the final 2 hours of dialysis is as safe and effective as that performed earlier. The smaller reduction in postdialysis systolic blood pressure in the late-exercise group may suggest a time-related clinical benefit.
DESIGN: A single-blind, randomized controlled clinical trial.
SETTING: Hospital-based hemodialysis unit.
PARTICIPANTS: Forty-two patients (N=42) on hemodialysis were randomly assigned to early- or late-exercise groups.
INTERVENTIONS: Both groups performed the same resistance exercise protocol during either the first or last 2 hours of dialysis for 8 weeks.
MAIN OUTCOME MEASURES: The primary outcomes were postdialysis systolic blood pressure and the number of intradialytic hypotensive episodes. Secondary outcomes included physical performance and lower extremity muscle strength.
RESULTS: Postdialysis systolic blood pressure declined less in the late-exercise group than in the early exercise group (interaction effect: -5.4 mmHg; 95% CI, -10.72 to -0.25; P<.05). No significant difference in the number of intradialytic hypotensive episodes was observed between the groups (P>.05). Both groups showed significant improvements in blood pressure, heart rate, and physical performance (P<.05). Significant improvement was observed only in the left quadriceps femoris muscle in both groups (P<.05).
CONCLUSIONS: Resistance exercise performed in the final 2 hours of dialysis is as safe and effective as that performed earlier. The smaller reduction in postdialysis systolic blood pressure in the late-exercise group may suggest a time-related clinical benefit.