Lepas anatifera as a biomonitor of ocean health, ecological impacts, and cancer risk in a new frontier of exploration (Brazilian Equatorial Margin).

For the first time, a comprehensive evaluation was carried out to assess the presence of banned, restricted, and widely used permitted pesticides in Lepas anatifera, a globally distributed oceanic species. This study aims to shed light on ocean health along Brazil's equatorial margin, a region identified as a priority for future exploration. Additionally, it seeks to contribute to the understanding of the South Atlantic Ocean, a region with limited scientific studies, by evaluating the potential risks associated with the ingestion of these barnacles. Specifically, the study investigates their potential role in cancer development or disruptions to the endocrine system, considering their critical position within the oceanic food web. A total of 60 organic pollutant compounds were analyzed in 1903 individuals distributed in 19 sample groups of L. anatifera using gas chromatography (GC) equipped with both an electron capture detector (ECD) and a nitrogen-phosphorus detector (NPD) (GC-ECD/NPD). The highest total concentration of permitted pesticides in L. anatifera was triazines (ƩTPs = 2314.87 ng/g), followed by organophosphorus (ƩOPPs = 231.86 ng/g) and pyrethroids (ƩPPs = 32.45 ng/g). Among banned and restricted substances, organochlorine pesticides (ƩOCPs = 24.30 ng/g) had the highest concentrations, followed by polybrominated diphenyl ethers (ƩPBDEs = 10.23 ng/g) and polychlorinated biphenyls (ƩPCBs = 6.01 ng/g). The cancer risk from polychlorinated biphenyls (PCBs) and organochlorine pesticides (OCPs) was considered insignificant or acceptable. L. anatifera is highlighted as an excellent oceanic biomonitor, demonstrating the ability to accumulate various traditional and emerging organic contaminants, necessitating improved waste management policies and monitoring plans. While PCBs and OCPs are well-known for causing severe diseases such as cancer, all the substances analyzed in this study have the potential to disrupt the endocrine and immune systems and impair reproductive functions. Some may even lead to feminization in animals, among other adverse health effects. These findings highlight the urgent need for effective policies and actions to improve the management of solid and liquid waste, alongside comprehensive plans to monitor the environmental fate of these substances and assess their true risks to living organisms.