[Clinical practice guidelines for the diagnosis, treatment, and prevention of Helicobacter pylori infection in Chinese adults].

Helicobacter pylori infection remains a significant public health concern in China. Effective prevention and control require a coordinated "three-in-one" approach encompassing standardized expert recommendations, consistent physician implementation, and active patient participation. However, comprehensive, systematic, and scientifically robust clinical practice guidelines for Helicobacter pylori infection to support clinical decision-making have been lacking. This guideline adopts a "from practice to practice" development framework, systematically identifying key clinical questions through extensive investigation and adhering to rigorous methodological standards to formulate practical, evidence-based recommendations. The multidisciplinary expert panel, incorporating perspectives from front-line clinicians, ensures that recommendations address real-world considerations, including resource availability, operational feasibility, and social ethics of healthcare. The development of this guideline directly addresses the critical bottleneck of the disconnect between consensus guidelines and clinical practice in current treatment and prevention efforts. While upholding the rigorous evidence-based medicine principle, it innovatively integrates with clinical practice needs, transforming complex bodies of professional evidence into clear, concise, and actionable key points. This guideline includes 45 key clinical topics and aims to serve as a bridge between professional medical evidence and healthcare practice, promote standardized, uniform clinical services, and enhance the overall prevention and control of Helicobacter pylori infection in China.