Clinical application of laparoscopic pectopexy in the treatment of pelvic organ prolapse: efficacy and safety.

OBJECTIVE

To evaluate the efficacy and safety of laparoscopic pectopexy in the treatment of female pelvic organ prolapse (POP).

METHODS

A total of 40 patients with anterior and/or apical compartment prolapse who underwent laparoscopic pectopexy at the First Affiliated Hospital of Zhengzhou University from January 2022 to June 2023 were included in this retrospective study. Clinical data and outcomes were collected and analyzed. Pelvic Organ Prolapse Quantification (POP-Q), patients global impression of improvement (PGI-I), pelvic floor distress inventory-20 (PFDI-20), pelvic organ prolapse/urinary incontinence sexual questionnaire-12 (PISQ-12), and generalized anxiety disorder 7-item (GAD-7) scale were applied to evaluate the subjective and objective response by postoperative quality of life and sexual function. Intraoperative and postoperative complications were also analyzed to evaluate surgical safety.

RESULTS

All the 40 patients successfully completed the operation without intraoperative complications. During regular follow-up, one case had urinary retention after the operation, one case (2.5%) had mesh exposure and two cases (5.0%) had chronic pelvic pain. The objective and subjective response rates were 97.5% and 90% at 3 months after operation, 87.5% and 87.5% at 12 months after operation, respectively. The scores of PISQ-12, PFDI-20, and GAD-7 at 12 months after operation were significantly improved when compared with those before operation (P < 0.05).

CONCLUSION

Laparoscopic pectopexy is an alternative safe and effective surgical approach for the treatment of POP with anterior and apical pelvic defects. This surgical approach effectively restore the pelvic anatomy, and significantly improved quality of life and sexual function.